WNT3A |
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معرفات |
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أسماء بديلة | WNT3A, Wnt family member 3A |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 606359 MGI: MGI:98956 HomoloGene: 22528 GeneCards: 89780 |
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علم الوجود الجيني |
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وظائف جزيئية | • protein domain specific binding • signaling receptor binding • co-receptor binding • GO:0005110 frizzled binding • GO:0001948، GO:0016582 ربط بروتيني • GO:0001105 transcription coactivator activity • receptor ligand activity |
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مكونات خلوية | • endocytic vesicle membrane • endoplasmic reticulum lumen • الفراغ خارج الخلية • cell surface • حويصلة خارج خلوية • Wnt-Frizzled-LRP5/6 complex • early endosome membrane • غشاء خلوي • تجويف غولجي • presynapse • خارج خلوي • مشبك عصبي • glutamatergic synapse |
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عمليات حيوية | • تكون الجسيدات • cellular response to retinoic acid • تكون الدم • positive regulation of protein phosphorylation • Wnt signaling pathway involved in forebrain neuroblast division • positive regulation of skeletal muscle tissue development • positive regulation of receptor internalization • axis elongation involved in somitogenesis • positive regulation of collateral sprouting in absence of injury • تطور الثدي • platelet activation • heart looping • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of protein localization to plasma membrane • cardiac muscle cell fate commitment • mesoderm development • cell proliferation in forebrain • positive regulation of mesodermal cell fate specification • negative regulation of fat cell differentiation • canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment • regulation of microtubule cytoskeleton organization • negative regulation of dopaminergic neuron differentiation • cell proliferation in midbrain • in utero embryonic development • negative regulation of axon extension involved in axon guidance • positive regulation of peptidyl-serine phosphorylation • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated • regulation of axonogenesis • positive regulation of B cell proliferation • post-anal tail morphogenesis • positive regulation of cardiac muscle cell differentiation • negative regulation of neuron projection development • paraxial mesodermal cell fate commitment • negative regulation of neurogenesis • positive regulation of protein tyrosine kinase activity • positive regulation of DNA-binding transcription factor activity • extracellular matrix organization • positive regulation of neural precursor cell proliferation • synaptic vesicle recycling • osteoblast differentiation • skeletal muscle cell differentiation • COP9 signalosome assembly • dorsal/ventral neural tube patterning • positive regulation of protein binding • platelet aggregation • midbrain development • positive regulation of protein kinase activity • positive regulation of cell-cell adhesion mediated by cadherin • positive regulation of hepatocyte proliferation • تخلق النسيج العصبي • spinal cord association neuron differentiation • axonogenesis • GO:0032737 positive regulation of cytokine production • positive regulation of dermatome development • somatic stem cell division • positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation • axon guidance • نمو متعدد الخلايا • determination of left/right symmetry • inner ear morphogenesis • ضبط زيادي للتكاثر الخلوي • regulation of cell differentiation • hippocampus development • negative regulation of heart induction by canonical Wnt signaling pathway • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني • نقل شاردة الكالسيوم • Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation • beta-catenin destruction complex disassembly • neuron differentiation • بروتين دبيلو.أن.تي • positive regulation of canonical Wnt signaling pathway • GO:1901313 positive regulation of gene expression • calcium ion transmembrane transport via low voltage-gated calcium channel • presynapse assembly • negative regulation of neuron death • positive regulation of core promoter binding • regulation of RNA biosynthetic process • regulation of signaling receptor activity • تكاثر خلوي • canonical Wnt signaling pathway • secondary palate development • cell fate commitment • modulation of chemical synaptic transmission • GO:1904739 regulation of synapse organization • postsynapse to nucleus signaling pathway • regulation of presynapse assembly |
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المصادر:Amigo / QuickGO | |
نمط التعبير عن الحمض النووي الريبوزي |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PBB_GE_WNT3A_gnf1h01091_at_fs.png/220px-PBB_GE_WNT3A_gnf1h01091_at_fs.png) |
المزيد من بيانات التعبير المرجعية |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 89780 | 22416 |
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Ensembl | ENSG00000154342 | ENSMUSG00000009900 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | |
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RefSeq (بروتين) | | XP_011542621 NP_149122، XP_011542621 |
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الموقع (UCSC | n/a | Chr 11: 59.14 – 59.18 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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