UBAP2L

Protein-coding gene in the species Homo sapiens
UBAP2L
Identifiers
AliasesUBAP2L, NICE-4, NICE4, ubiquitin associated protein 2 like
External IDsOMIM: 616472; MGI: 1921633; HomoloGene: 40988; GeneCards: UBAP2L; OMA:UBAP2L - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for UBAP2L
Genomic location for UBAP2L
Band1q21.3Start154,220,179 bp[1]
End154,271,510 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for UBAP2L
Genomic location for UBAP2L
Band3 F1|3Start89,907,447 bp[2]
End89,959,935 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • left ovary

  • right ovary

  • skin of abdomen

  • skin of leg

  • right lung

  • canal of the cervix

  • gastric mucosa

  • body of uterus

  • upper lobe of left lung
Top expressed in
  • tail of embryo

  • genital tubercle

  • spermatid

  • neural layer of retina

  • somite

  • yolk sac

  • spermatocyte

  • Rostral migratory stream

  • epiblast

  • ventricular zone
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • protein binding
  • RNA binding
Cellular component
  • PcG protein complex
  • cytoplasm
  • nucleus
Biological process
  • hematopoietic stem cell homeostasis
  • binding of sperm to zona pellucida
  • positive regulation of gene expression
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9898

74383

Ensembl

ENSG00000143569

ENSMUSG00000042520

UniProt

Q14157

Q80X50

RefSeq (mRNA)
NM_001127320
NM_001287815
NM_001287816
NM_014847
NM_001330730

NM_001375612
NM_001375614
NM_001375615
NM_001375616
NM_001375617
NM_001375618
NM_001375619
NM_001375620
NM_001375621
NM_001375622
NM_001375623
NM_001375624
NM_001375625
NM_001375626
NM_001375627
NM_001375628
NM_001375629
NM_001375630
NM_001375631

NM_001165983
NM_001165984
NM_001165985
NM_001165986
NM_001165987

NM_001165988
NM_028475
NM_153489
NM_001357307

RefSeq (protein)
NP_001120792
NP_001274744
NP_001274745
NP_001317659
NP_055662

NP_001362541
NP_001362543
NP_001362544
NP_001362545
NP_001362546
NP_001362547
NP_001362548
NP_001362549
NP_001362550
NP_001362551
NP_001362552
NP_001362553
NP_001362554
NP_001362555
NP_001362556
NP_001362557
NP_001362558
NP_001362559
NP_001362560

NP_001159455
NP_001159456
NP_001159457
NP_001159458
NP_001159459

NP_001159460
NP_082751
NP_705693
NP_001344236

Location (UCSC)Chr 1: 154.22 – 154.27 MbChr 3: 89.91 – 89.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquitin-associated protein 2-like is a protein that in humans is encoded by the UBAP2L gene.[5][6][7]


Interactions

UBAP2L has been shown to interact with BAT2.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143569 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042520 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Seki N, Tanaka A, Ishikawa K, Nomura N (Mar 1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. doi:10.1093/dnares/2.4.167. PMID 8590280.
  6. ^ Marenholz I, Zirra M, Fischer DF, Backendorf C, Ziegler A, Mischke D (Mar 2001). "Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library". Genome Res. 11 (3): 341–55. doi:10.1101/gr.114801. PMC 311024. PMID 11230159.
  7. ^ "Entrez Gene: UBAP2L ubiquitin associated protein 2-like".
  8. ^ Lehner, Ben; Semple Jennifer I; Brown Stephanie E; Counsell Damian; Campbell R Duncan; Sanderson Christopher M (Jan 2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1). United States: 153–67. doi:10.1016/S0888-7543(03)00235-0. ISSN 0888-7543. PMID 14667819.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
  • Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
  • Tao WA, Wollscheid B, O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8): 591–8. doi:10.1038/nmeth776. PMID 16094384. S2CID 20475874.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
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  • 1wj7: Solution structure of RSGI RUH-015, a UBA domain from mouse cDNA
    1wj7: Solution structure of RSGI RUH-015, a UBA domain from mouse cDNA


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